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Dialectic Therapeutics Receives $14M Cancer Research Award
A Texas-based biotech firm focused on cancer treatments, Dialectic Therapeutics Inc., recently received a $14.4 million Texas Company (TXCO) Product Development Research Award from the Cancer Prevention and Research Institute of Texas (CPRIT). Dialectic will use the funding to further advance the clinical development of its lead product candidate, DT2216, a unique compound built using the Antiapoptotic Protein Targeted Degradation (APTaD) technology platform.
This grant adds to the initial $3 million seed award that Dialectic received from CPRIT in 2020, which was instrumental in supporting preclinical studies. These studies demonstrate that DT2216 selectively induces the degradation of B-cell lymphoma extra-large or BCL-XL in cancer cells. This either stimulates the return of cellular apoptosis or sensitizes the cells to be more susceptible to chemotherapy and thus cellular destruction.
- ◦Financing