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Boston & New England  + Boston  + Office  | 
Breakthrough Properties has opened The 105 by Breakthrough, a life science office-and-lab facility in Boston, MA.

Breakthrough Properties Opens 264K-SF, Fully Leased Life-Science Property in Boston

Breakthrough Properties has opened The 105 by Breakthrough, a 263,500-square-foot life science office-and-lab facility in Boston, MA, in collaboration with CRISPR Therapeutics. The property is fully leased to CRISPR Therapeutics and will serve as that company’s new US research and development headquarters.

The 105 was developed to meet LEED Gold and Fitwel Certification standards and which features massive lab-enabled floorplates, floor-to-ceiling glass, multiple outdoor terraces, a fitness center and an indoor bicycle room.  The ground floor is designed for a range of community activities and features a publicly accessible café, multi-use innovation space and a thruway for public foot traffic.

The 105 is one of several Boston-area developments currently in the Breakthrough portfolio:

  • One Canal by Breakthrough is a four-story, 105,000-square-foot lab and office redevelopment in East Cambridge.
  • Breakthrough’s team is involved in the design and development of the modern life sciences facilities within the 14-acre Enterprise Research Campus in Boston.
  • Breakthrough is involved in the ground-up development at 232 A Street on a portion of Gillette’s former world headquarters along the South Boston waterfront.

Breakthrough Properties was formed in 2019 as a joint venture between global real estate owner, developer and investor Tishman Speyer and biotechnology investment firm Bellco Capital.


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About Lisa McDuffie

Lisa McDuffie arrives at ConnectCRE via REALTOR® world, where she served for nearly two decades as communications director for one of the nation’s largest REALTOR® organizations. She supported two membership-elected presidents who were commercial real estate practitioners, and managed the communications initiatives of the organization’s commercial special interest group. When not following the latest commercial real estate news, Lisa is zeroed in on her charismatic off-the-track thoroughbred as she makes the transition from an utterly failed racehorse to a lovely show hunter.

  • ◦Development