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Boston & New England  + Metro Boston  + Healthcare  |  October 1, 2026
Paul Bubny
By: Paul Bubny

Mass General Brigham Leases 100K SF as New Lab Building’s First Tenant

Mass General Brigham (MGB) has leased approximately 100,000 square feet of lab space on the lower floors of Greystar’s 74M at 74 Middlesex Ave. in Somerville, MA, becoming the property’s first tenant. The building will house MGB’s central pathology laboratory services, consolidating existing pathology functions from across the system.

Formerly an industrial brownfield site, 74M now contains 469,000 square feet of purpose-built lab and office space across 15 stories. One move-in-ready spec suite remains, according to Greystar.

“As we see renewed demand for lab space across the region, we believe the building is well positioned to expand its tenant base with groups looking to attract top talent to the broader Assembly Square innovation hub,” said Matt DeNoble, senior director of investment management at Greystar. “We are thrilled to welcome Mass General Brigham to the 74M community and look forward to supporting the healthcare organization as they expand their research and lab foothold in the region.”

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About Paul Bubny

Paul Bubny serves as Senior Content Director for Connect Commercial Real Estate, a role to which he brings 16-plus years’ experience covering the commercial real estate industry and 30-plus years in business-to-business journalism. In this capacity, he oversees daily operations while also reporting on both local/regional markets and national trends, covering individual transactions across all property types, as well as delving into broader subject matter. He produces 7-10 daily news stories per day and works with the Connect team and clients to develop longer-form content, ranging from Q&As to thought-leadership pieces. Prior to joining Connect, Paul was Managing Editor for both Real Estate Forum and GlobeSt.com at American Lawyer Media, where he oversaw operations at both publications while also producing daily news and feature-length articles. His tenure in B2B publishing stretches back into the print era, and he has served as Editor in Chief on four national trade publications. Since 1999, Paul has volunteered as the newsletter editor of passenger rail advocacy groups (one national, one local).
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